Behavioral depression during cocaine withdrawal is associated with decreased spontaneous activity of ventral tegmental area dopamine neurons.

Withdrawal from an escalating-dose, bingelike regimen of cocaine administration in rats produced significantly depressed levels of locomotor activity during the nocturnal portion of the day-night cycle. This effect was observed during the first 48 hrs of testing. Extracellular single-unit recordings of ventral tegmental area (VTA) dopamine (DA) neurons revealed no differences between saline- and cocaine-treated rats with respect to basal firing rates. However, significantly fewer spontaneously active VTA DA neurons were encountered in rats withdrawn from binge cocaine. As with the nocturnal hypoactivity, this effect was observed only during the first 48 hrs of withdrawal. These findings suggest that short-term DA neuron dysfunction during cocaine withdrawal temporally corresponds to behavioral disruptions that are similar to those described in human addicts. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

鄂尔多斯盆地姬塬-堡子湾地区长4+5油层成岩作用与储层评价

利用岩石铸体薄片鉴定、X射线衍射分析、扫描电镜分析等测试手段，对鄂尔多斯盆地姬塬一堡子湾地区延长组长4＋5油层储集岩的岩石学特征、成岩作用和物性特征进行了分析。结果表明，该储集岩为细粒的长石砂岩和岩屑长石砂岩，颗粒呈次棱角状，成分成熟度普遍较低，结构成熟度中等一较好；经历了压实、胶结、压溶和溶解等一系列成岩作用；储集岩具有低孔、低渗的特点。在以上研究基础上，结合压汞分析、孔隙组合分析，对储层进行综合评价认为，长4＋5储层可分为4类，研究区以Ⅱ、Ⅲ类（中等一差）储层为主。     

香豆胶衍生物的化学结构及稳定性研究

将市售商品溶于水,用异丙醇沉析提纯,溶于0.1 mol/L NaNO3纯水溶液中,经0.5μm滤膜过滤后用水相凝胶渗透色谱法(GPC)测定,测得香豆胶(FG)、羟丙基香豆胶(HPFG)、阳离子香豆胶(CFG)的数均、重均相对分子质量Mn、Mw分别为:1.19×105、3.36×105,8.52×104、2.85×105,9.33×104、2.87×105。用甘露聚糖链在碱性条件下醚化时发生降解,解释两种改性FG的相对分子质量较FG低而多分散性(Mw/Mn)较FG高的测试结果。认为商品FG的1%水溶液黏度(1300 mPa.s)高于商品HPFG和CFG(分别为705和610 mPa.s)的原因是前者相对分子质量较高且残渣含量也较高(~10%,后二者为1%~2%)。HPFG的取代度为0.12,根据文献发表的13C-NMR数据确认HPFG分子链上羟丙基取代位置为C6。讨论了香豆胶(半乳甘露聚糖)的化学结构。热重分析法测定的热稳定性,HPFG高于CFG,CFG又高于FG。图6表3参13。     

铁通资源管理系统的设计和实现

在分析铁路通信资源结构的基础上,利用地理信息系统技术、数据库技术和客户/服务器(C/S)模式,为铁通(ChinaTietong)各级分公司和运营部门提供一套较为完善的资源管理信息系统。文中分析了铁通资源的结构与资源之间的关联,介绍了系统功能、物理结构及体系结构,详细分析了数据库设计、地理信息系统和系统安全性所采用的关键技术。这套系统的应用对铁通网络管理的现代化将起到重要的推动作用。     

X-Ray Measurement of Residual Stress in Plastic Bonded Explosives

The X-ray diffractive technology was adopted for tentative study of plastic bonded explosive. The datum of some new diffractive peaks in standard PDF cards were added. The effects of strain to interplanar distance and crystal size of the explosive were studied. The results show that grain size of plastic bonded explosive is decreasing with the increasing of the pressure, and the residual stress of the explosive is draw stress.     

A Novel Segmentation and Feedback Model for Resolving Contention in Optical Burst Switching

A novel segmentation and feedback model (SFM) applied to resolve contention is proposed. Simulation and performance analyses show that the SFM effectively avoids contentions in optical burst switching (OBS). The long delay time of deflection routing and the immature technology of wavelength converters and optical buffers are not deployed in the SFM. The SFM does not only realize fast switching but also allows preemption by higher priority bursts.     

First Harmonic (2f) Characterisation of Resonant Frequency and Q-Factor of Micromechanical Transducers

In this paper, the response to the first harmonic component (2f) of the electrostatic force in single terminal driven electrostatic comb-drive and parallel-plate drive was used as a signal to extract device parameters, namely, the Q-factor and resonant frequency instead of the fundamental (1f) resonance response. It is shown that the difficulty in motional measurement due to electrical cross-talk (parasitics) using 1f measurement can be overcome with a higher signal-to-noise ratio of the 2f signal. Both atmospheric (low-Q) and reduced pressure environment were investigated using off-chip electronics and lock-in amplifier. The measurements were done on the electrostatic comb-drive and capacitive parallel plate sensing plates that form the two core modules of a yaw rate sensor (dual-axis resonator). The effects of AC and DC bias voltages on the measured response have been investigated. Experimental amplitude and phase response data have been analysed using the Lorentzian curve-fit, Resonance Curve Area (RCA) method, the half-power bandwidth method (3 dB) and the Nyquist plot for data fitting and determination of the Q-factor and resonance frequency.     

盘石头水库河槽段趾板基岩的地质概况与防渗设计分析

盘石头水库河槽段趾板基岩建基面下8m为相对不透水层,如按常规进入不透水层5m设计帷幕,深度只有13m左右,对100m高坝而言,深度偏浅,为安全考虑,帷幕设计为悬挂式帷幕,主帷幕深度按1/3坝高考虑,穿透隔水层,隔水层以上以一排主帷幕和两排副帷幕防渗,隔水层以下以一排主帷幕防渗。     

关于气井产能、气田稳产特征和气区开采潜力的探讨

根据气田开发特点和国内外开发实践，对气田平均产能评价方法、开发速度与稳产的关系以及气区开采潜力等问题进行了探讨，以提高开发评价、开发建设及投资决策的科学性与可靠性，达到高效开发和稳定供气的目的。分析评价了国内外常用的6种气井产能评价方法，指出了其适用条件。利用中国、土库曼斯坦和俄罗斯部分开发历史较长的气田开发实例分析了开发速度与稳产的关系，结果表明四川裂缝系统稳产情况最好，而土库曼斯坦气田稳产关系最差。利用俄罗斯已枯竭老气区、正在开发的大型主力气区以及中国四川开采历史较长气区的开发实例，对气区开采潜力进行综合分析和探讨，认为在预测气田（或气区）的开发潜力、稳定供气水平和年限时，要全面评价、预计尚未探明储量的规模、质量、投产时间、投产顺序以及储量的可信度和可靠性，以降低开发决策的风险，提高中、长期开发规划的科学性。图5表2参10     

苏北及邻区前志留基础层的综合地球物理研究

在前新生代油气资源选区评价中，前志留面之下未变质沉积地层（简称前志留基础层）的分布具有重要的参考价值。从提高纵向分辨率的处理和反演技术的应用入手，结合约束条件,利用大地电磁测深数据反演,揭示前志留面等界面的埋深和分布；同时应用小波分析技术，从磁场中分解出区域磁异常，反演结晶基底的埋深。通过这2个界面埋深的差异来分析前志留基础层的分布